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Axonal Targeting of Trk Receptors via Transcytosis Regulates Sensitivity to Neurotrophin Responses

Axonal targeting of trophic receptors is critical for neuronal responses to extracellular developmental cues, yet the underlying trafficking mechanisms remain unclear. Here, we report that tropomyosin-related kinase (Trk) receptors for target-derived neurotrophins are anterogradely trafficked to axo...

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Hlavní autoři: Ascaño, Maria, Richmond, Alissa, Borden, Philip, Kuruvilla, Rejji
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775807/
https://ncbi.nlm.nih.gov/pubmed/19759314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1542-09.2009
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