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Isoform-specific dephosphorylation of dynamin1 by calcineurin couples neurotrophin receptor endocytosis to axonal growth

Endocytic events are critical for neuronal survival in response to target-derived neurotrophic cues, but whether local axon growth is mediated by endocytosis-dependent signaling mechanisms remains unclear. Here, we report that Nerve Growth Factor (NGF) promotes endocytosis of its TrkA receptors and...

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Detalhes bibliográficos
Main Authors: Bodmer, Daniel, Ascaño, Maria, Kuruvilla, Rejji
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119854/
https://ncbi.nlm.nih.gov/pubmed/21689596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.04.025
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