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Coarse-grained Simulations of Conformational Changes in Multidrug Efflux Transporter AcrB

The multidrug resistance (MDR) system actively pumps the antibiotics out of cells causing serious health problems. During the pumping, AcrB (one of the key MDR components), undergoes a series of large-scale and proton-motive conformational changes. Capturing the conformational changes through all-at...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Jewel, Yead, Liu, Jin, Dutta, Prashanta
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614849/
https://ncbi.nlm.nih.gov/pubmed/28770910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mb00276a
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