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Coarse-grained Simulations of Conformational Changes in Multidrug Efflux Transporter AcrB
The multidrug resistance (MDR) system actively pumps the antibiotics out of cells causing serious health problems. During the pumping, AcrB (one of the key MDR components), undergoes a series of large-scale and proton-motive conformational changes. Capturing the conformational changes through all-at...
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| Udgivet i: | Mol Biosyst |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614849/ https://ncbi.nlm.nih.gov/pubmed/28770910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mb00276a |
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