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Axitinib in the treatment of renal cell carcinoma: design, development, and place in therapy
Since 2005, the approved first-line treatment of metastatic renal cell carcinoma consists in tyrosine kinase inhibitors (TKIs) targeting the vascular endothelial growth factor receptors (VEGFRs). Axitinib is an oral second-generation TKI and a potent VEGFR inhibitor with a half maximal inhibitory co...
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| Publicado no: | Drug Des Devel Ther |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614734/ https://ncbi.nlm.nih.gov/pubmed/29033542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S109640 |
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