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Cabozantinib in the treatment of advanced renal cell carcinoma: design, development, and potential place in the therapy

The treatment of metastatic renal cell carcinoma (mRCC) has markedly improved over the last few years with the introduction of several targeted agents in clinical practice. Nevertheless, either primary or secondary resistance to inhibition of VEGF and mTOR pathways has limited the clinical benefit o...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Grassi, Paolo, Verzoni, Elena, Ratta, Raffaele, Mennitto, Alessia, de Braud, Filippo, Procopio, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939993/
https://ncbi.nlm.nih.gov/pubmed/27462141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S104225
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