nsPEF-induced PIP(2) depletion, PLC activity and actin cytoskeletal cortex remodeling are responsible for post-exposure cellular swelling and blebbing

Cell swelling and blebbing has been commonly observed following nanosecond pulsed electric field (nsPEF) exposure. The hypothesized origin of these effects is nanoporation of the plasma membrane (PM) followed by transmembrane diffusion of extracellular fluid and disassembly of cortical actin structu...

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Foilsithe in:Biochem Biophys Rep
Main Authors: Tolstykh, Gleb P., Thompson, Gary L., Beier, Hope T., Steelman, Zachary A., Ibey, Bennett L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614542/
https://ncbi.nlm.nih.gov/pubmed/28955986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.11.005
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