nsPEF-induced PIP2 depletion, PLC activity and actin cytoskeletal cortex remodeling are responsible for post-exposure cellular swelling and blebbing

Cell swelling and blebbing has been commonly observed following nanosecond pulsed electric field (nsPEF) exposure. The hypothesized origin of these effects is nanoporation of the plasma membrane (PM) followed by transmembrane diffusion of extracellular fluid and disassembly of cortical actin structu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gleb P. Tolstykh, Gary L. Thompson, Hope T. Beier, Zachary A. Steelman, Bennett L. Ibey
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-03-01
Colecção:Biochemistry and Biophysics Reports
Assuntos:
Nanosecond pulsed electric field
Nanopores
PIP2 hydrolysis
Cellular swelling and blebbing
Calcium
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405580816302898
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados