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Replicative Bypass Studies of α-Anomeric Lesions of 2′-Deoxyribonucleosides in Vitro

Genomic integrity is constantly challenged by a variety of endogenous and exogenous DNA damaging agents, which can lead to the formation of 10(4)–10(5) DNA lesions per cell per day. Reactive oxygen species (ROS) represent a major type of DNA damaging agent. Specifically, a hydroxyl radical can attac...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Williams, Nicole L., Amato, Nicholas J., Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614518/
https://ncbi.nlm.nih.gov/pubmed/28388097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00439
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