Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes

The immunological mechanism(s) of action whereby teplizumab preserves C-peptide levels in the progression of patients with recent onset type 1 diabetes (T1D) is still not well understood. In the present study, we evaluated the kinetics of T cell modulation in peripheral blood following two 14-day co...

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Veröffentlicht in:Cell Immunol
Hauptverfasser: Long, S. Alice, Thorpe, Jerill, Herold, Kevan C., Ehlers, Mario, Sanda, Srinath, Lim, Noha, Linsley, Peter S., Nepom, Gerald T., Harris, Kristina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614459/
https://ncbi.nlm.nih.gov/pubmed/28844471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.07.007
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