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Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetase

γ-glutamylcysteine synthetase (Gcs) is a vital enzyme catalyzing the first and rate limiting step in the trypanothione biosynthesis pathway, the ATP-dependent ligation of L-Glutamate and L-Cysteine to form gamma-glutamylcysteine. The Trypanothione biosynthesis pathway is unique metabolic pathway ess...

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Bibliografski detalji
Izdano u:Biochem Biophys Rep
Glavni autori: Agnihotri, Pragati, Singh, Saurabh P., Shakya, Anil Kumar, Pratap, J. Venkatesh
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613772/
https://ncbi.nlm.nih.gov/pubmed/28955948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.08.016
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