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Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetase
γ-glutamylcysteine synthetase (Gcs) is a vital enzyme catalyzing the first and rate limiting step in the trypanothione biosynthesis pathway, the ATP-dependent ligation of L-Glutamate and L-Cysteine to form gamma-glutamylcysteine. The Trypanothione biosynthesis pathway is unique metabolic pathway ess...
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| Veröffentlicht in: | Biochem Biophys Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613772/ https://ncbi.nlm.nih.gov/pubmed/28955948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.08.016 |
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