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Biochemical and biophysical characterization of Leishmania donovani gamma-glutamylcysteine synthetase
γ-glutamylcysteine synthetase (Gcs) is a vital enzyme catalyzing the first and rate limiting step in the trypanothione biosynthesis pathway, the ATP-dependent ligation of L-Glutamate and L-Cysteine to form gamma-glutamylcysteine. The Trypanothione biosynthesis pathway is unique metabolic pathway ess...
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Publicado no: | Biochem Biophys Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613772/ https://ncbi.nlm.nih.gov/pubmed/28955948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.08.016 |
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