Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy

Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect of genetic background on phenotype in two lines of transgenic mice bearing the same...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Panayiotou, E., Papacharalambous, R., Antoniou, A., Christophides, G., Papageorgiou, L., Fella, E., Malas, S., Kyriakides, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613746/
https://ncbi.nlm.nih.gov/pubmed/28955941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.08.005
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