Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy

Hereditary ATTR V30M amyloidosis is a lethal autosomal dominant sensorimotor and autonomic neuropathy caused by deposition of aberrant transthyretin (TTR). Immunohistochemical examination of sural nerve biopsies in patients with amyloidotic neuropathy show co-aggregation of TTR with several proteins...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Mol Neurosci
Prif Awduron: Fella, Eleni, Sokratous, Kleitos, Papacharalambous, Revekka, Kyriacou, Kyriacos, Phillips, Joy, Sanderson, Sam, Panayiotou, Elena, Kyriakides, Theodoros
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423984/
https://ncbi.nlm.nih.gov/pubmed/28539873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00138
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