Genomic instability during reprogramming by nuclear transfer is DNA replication dependent

Somatic cells can be reprogrammed to a pluripotent state by nuclear transfer into oocytes, yet developmental arrest often occurs. While incomplete transcriptional reprogramming is known to cause developmental failure, reprogramming also involves concurrent changes in cell cycle progression and nucle...

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Detaylı Bibliyografya
Yayımlandı:Nat Cell Biol
Asıl Yazarlar: Chia, Gloryn, Agudo, Judith, Treff, Nathan, Sauer, Mark V., Billing, David, Brown, Brian D., Baer, Richard, Egli, Dieter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613662/
https://ncbi.nlm.nih.gov/pubmed/28263958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3485
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