Coordination of changes in expression and phosphorylation of eukaryotic elongation factor 2 (eEF2) and eEF2 kinase in hypertrophied cardiomyocytes

Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is one of the Ca(2+)/calmodulin-dependent protein kinases. Activated eEF2K phosphorylates its specific substrate, eEF2, which results in inhibition of protein translation. We have recently shown that protein expression of eEF2K was specifically in...

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Udgivet i:Biochem Biophys Rep
Main Authors: Kameshima, Satoshi, Okada, Muneyoshi, Ikeda, Shiro, Watanabe, Yuki, Yamawaki, Hideyuki
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613342/
https://ncbi.nlm.nih.gov/pubmed/28955910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.06.018
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