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Population Pharmacokinetic and Pharmacodynamic Modeling of LY2510924 in Patients With Advanced Cancer

The objectives of this study were to characterize the pharmacokinetics (PK) of LY2510924, a potent peptide antagonist of the CXCR4 receptor, after subcutaneous administration in patients with advanced cancer forms and quantify LY2510924 stimulatory effects on the mobilization of cells bearing the cl...

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Dades bibliogràfiques
Publicat a:CPT Pharmacometrics Syst Pharmacol
Autors principals: Bihorel, S, Raddad, E, Fiedler‐Kelly, J, Stille, JR, Hing, J, Ludwig, E
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613202/
https://ncbi.nlm.nih.gov/pubmed/28643374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12221
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