Distinct mobilization of leukocytes and hematopoietic stem cells by CXCR4 peptide antagonist LY2510924 and monoclonal antibody LY2624587

Stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 play a critical role in mobilization and redistribution of immune cells and hematopoietic stem cells (HSCs). We evaluated effects of two CXCR4-targeting agents, peptide antagonist LY2510924 and monoclonal antibody LY2624587, on mobilizing...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Peng, Sheng-Bin, Van Horn, Robert D., Yin, Tinggui, Brown, Robin M., Roell, William C., Obungu, Victor H., Ruegg, Charles, Wroblewski, Victor J., Raddad, Eyas, Stille, John R.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706900/
https://ncbi.nlm.nih.gov/pubmed/29212254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21816
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