Insulin Prevents Aberrant Mitochondrial Phenotype in Sensory Neurons of Type 1 Diabetic Rats

Diabetic neuropathy affects approximately 50% of diabetic patients. Down-regulation of mitochondrial gene expression and function has been reported in both human tissues and in dorsal root ganglia (DRG) from animal models of type 1 and type 2 diabetes. We hypothesized that loss of direct insulin sig...

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Gepubliceerd in:Exp Neurol
Hoofdauteurs: Aghanoori, Mohamad-Reza, Smith, Darrell R., Chowdhury, Subir Roy, Sabbir, Mohammad Golam, Calcutt, Nigel A., Fernyhough, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612919/
https://ncbi.nlm.nih.gov/pubmed/28803751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.08.005
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