Poly(N-(2-Hydroxypropyl) Methacrylamide)-Valproic Acid Conjugates as Block Copolymer Nanocarriers

We report nanoassemblies based on block copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) in which drug cleavage enhances the biological compatibility of the original polymer carrier by regeneration of HPMA units. Drug release via ester hydrolysis suggests this approach offers potential for st...

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Bibliographic Details
Published in:Polym Chem
Main Authors: Alfurhood, Jawaher A., Sun, Hao, Kabb, Christopher P., Tucker, Bryan S., Matthews, James H., Luesch, Hendrik, Sumerlin, Brent S.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612619/
https://ncbi.nlm.nih.gov/pubmed/28959359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C7PY00196G
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