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Predicting Gene Silencing Through the Spatiotemporal Control of siRNA Release from Photo-responsive Polymeric Nanocarriers

New materials and methods are needed to better control the binding vs. release of nucleic acids for a wide range of applications that require the precise regulation of gene activity. In particular, novel stimuli-responsive materials with improved spatiotemporal control over gene expression would unl...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Greco, Chad T., Epps,, Thomas H., Sullivan, Millicent O.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612584/
https://ncbi.nlm.nih.gov/pubmed/28784979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55803
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