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Efficient tuning of siRNA dose response by combining mixed polymer nanocarriers with simple kinetic modeling
Two of the most prominent challenges that limit the clinical success of siRNA therapies are a lack of control over cargo release from the delivery vehicle and an incomplete understanding of the link between gene silencing dynamics and siRNA dosing. Herein, we address these challenges through the for...
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| Pubblicato in: | Acta Biomater |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5317101/ https://ncbi.nlm.nih.gov/pubmed/28063990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.01.003 |
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