Light-Mediated Activation of siRNA Release in Diblock Copolymer Assemblies for Controlled Gene Silencing

Controllable release is particularly important for the delivery of small interfering RNA (siRNA), as siRNAs have a high susceptibility to enzymatic degradation if release is premature, yet lack silencing activity if they remain inaccessible within the cytoplasm. To overcome these hurdles, novel and...

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Vydáno v:Adv Healthc Mater
Hlavní autoři: Foster, Abbygail A., Greco, Chad T., Green, Matthew D., Epps, Thomas H., Sullivan, Millicent O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429132/
https://ncbi.nlm.nih.gov/pubmed/25530259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400671
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