Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate

From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to 5 continents and caused 8000 respiratory infections and 800 deaths. To ameliorate the effects of future outbreaks as well as to prepare for biodefense, a process for the production of a recombinant protein vac...

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Publicado no:J Pharm Sci
Main Authors: Chen, Wen-Hsiang, Chag, Shivali M., Poongavanam, Mohan V., Biter, Amadeo B., Ewere, Ebe A., Rezende, Wanderson, Seid, Christopher A., Hudspeth, Elissa M., Pollet, Jeroen, McAtee, C. Patrick, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. Published by Elsevier Inc. on behalf of the American Pharmacists Association®. 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612335/
https://ncbi.nlm.nih.gov/pubmed/28456726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.04.037
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