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The extracellular metalloprotease AdamTS-A anchors neural lineages in place within and preserves the architecture of the central nervous system

The extracellular matrix (ECM) regulates cell migration and sculpts organ shape. AdamTS proteins are extracellular metalloproteases known to modify ECM proteins and promote cell migration, but demonstrated roles for AdamTS proteins in regulating CNS structure and ensuring cell lineages remain fixed...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Skeath, James B., Wilson, Beth A., Romero, Selena E., Snee, Mark J., Zhu, Yi, Lacin, Haluk
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611953/
https://ncbi.nlm.nih.gov/pubmed/28760813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.145854
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