The extracellular metalloprotease AdamTS-A anchors neural lineages in place within and preserves the architecture of the central nervous system

The extracellular matrix (ECM) regulates cell migration and sculpts organ shape. AdamTS proteins are extracellular metalloproteases known to modify ECM proteins and promote cell migration, but demonstrated roles for AdamTS proteins in regulating CNS structure and ensuring cell lineages remain fixed...

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Detalles Bibliográficos
Publicado en:Development
Autores principales: Skeath, James B., Wilson, Beth A., Romero, Selena E., Snee, Mark J., Zhu, Yi, Lacin, Haluk
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611953/
https://ncbi.nlm.nih.gov/pubmed/28760813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.145854
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