The secreted AdamTS-A metalloprotease is required for collective cell migration

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during e...

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Bibliographic Details
Main Authors: Ismat, Afshan, Cheshire, Alan M., Andrew, Deborah J.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2013
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631971/
https://ncbi.nlm.nih.gov/pubmed/23536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087908
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