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The secreted AdamTS-A metalloprotease is required for collective cell migration

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during e...

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Autori principali: Ismat, Afshan, Cheshire, Alan M., Andrew, Deborah J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631971/
https://ncbi.nlm.nih.gov/pubmed/23536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087908
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