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The secreted AdamTS-A metalloprotease is required for collective cell migration

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during e...

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Bibliografske podrobnosti
Main Authors: Ismat, Afshan, Cheshire, Alan M., Andrew, Deborah J.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631971/
https://ncbi.nlm.nih.gov/pubmed/23536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087908
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