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The secreted AdamTS-A metalloprotease is required for collective cell migration

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during e...

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Détails bibliographiques
Auteurs principaux: Ismat, Afshan, Cheshire, Alan M., Andrew, Deborah J.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631971/
https://ncbi.nlm.nih.gov/pubmed/23536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087908
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