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The secreted AdamTS-A metalloprotease is required for collective cell migration

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during e...

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Bibliografiske detaljer
Main Authors: Ismat, Afshan, Cheshire, Alan M., Andrew, Deborah J.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631971/
https://ncbi.nlm.nih.gov/pubmed/23536567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087908
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