The Cerebrospinal Fluid Aβ(1–42)/Aβ(1–40) Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer’s Disease in a Clinical Setting

BACKGROUND: Evidence suggests that the concordance between amyloid-PET and cerebrospinal fluid (CSF) amyloid-β (Aβ) increases when the CSF Aβ(1–42)/Aβ(1–40) ratio is used as compared to CSF Aβ(1–42) levels alone. OBJECTIVE: In order to test this hypothesis, we set up a prospective longitudinal study...

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Publicat a:J Alzheimers Dis
Autors principals: Niemantsverdriet, Ellis, Ottoy, Julie, Somers, Charisse, De Roeck, Ellen, Struyfs, Hanne, Soetewey, Femke, Verhaeghe, Jeroen, Van den Bossche, Tobi, Van Mossevelde, Sara, Goeman, Johan, De Deyn, Peter Paul, Mariën, Peter, Versijpt, Jan, Sleegers, Kristel, Van Broeckhoven, Christine, Wyffels, Leonie, Albert, Adrien, Ceyssens, Sarah, Stroobants, Sigrid, Staelens, Steven, Bjerke, Maria, Engelborghs, Sebastiaan
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611891/
https://ncbi.nlm.nih.gov/pubmed/28869470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170327
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