The Cerebrospinal Fluid Aβ(1–42)/Aβ(1–40) Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer’s Disease in a Clinical Setting

BACKGROUND: Evidence suggests that the concordance between amyloid-PET and cerebrospinal fluid (CSF) amyloid-β (Aβ) increases when the CSF Aβ(1–42)/Aβ(1–40) ratio is used as compared to CSF Aβ(1–42) levels alone. OBJECTIVE: In order to test this hypothesis, we set up a prospective longitudinal study...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Niemantsverdriet, Ellis, Ottoy, Julie, Somers, Charisse, De Roeck, Ellen, Struyfs, Hanne, Soetewey, Femke, Verhaeghe, Jeroen, Van den Bossche, Tobi, Van Mossevelde, Sara, Goeman, Johan, De Deyn, Peter Paul, Mariën, Peter, Versijpt, Jan, Sleegers, Kristel, Van Broeckhoven, Christine, Wyffels, Leonie, Albert, Adrien, Ceyssens, Sarah, Stroobants, Sigrid, Staelens, Steven, Bjerke, Maria, Engelborghs, Sebastiaan
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611891/
https://ncbi.nlm.nih.gov/pubmed/28869470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170327
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