No added diagnostic value of non-phosphorylated tau fraction (p-tau(rel)) in CSF as a biomarker for differential dementia diagnosis

BACKGROUND: The Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ(1–42), t-tau, and p-tau(181) overlap with other diseases. New tau modifications or epitopes, such as the non-phosphorylated tau fraction (p-tau(rel)), may improve differential dementia diagnosis. The goal of this study...

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Vydáno v:Alzheimers Res Ther
Hlavní autoři: Goossens, Joery, Bjerke, Maria, Struyfs, Hanne, Niemantsverdriet, Ellis, Somers, Charisse, Van den Bossche, Tobi, Van Mossevelde, Sara, De Vil, Bart, Sieben, Anne, Martin, Jean-Jacques, Cras, Patrick, Goeman, Johan, De Deyn, Peter Paul, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513364/
https://ncbi.nlm.nih.gov/pubmed/28709448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0275-5
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