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Neuroprotection of dexmedetomidine against propofol-induced neuroapoptosis partly mediated by PI3K/Akt pathway in hippocampal neurons of fetal rat

The aim was to investigate how the PI3K/Akt pathway is involved in the protection of dexmedetomidine against propofol. The hippocampal neurons from fetal rats were separated and cultured in a neurobasal medium. Cell viability was assayed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromid...

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Detalhes bibliográficos
Publicado no:J Zhejiang Univ Sci B
Main Authors: Zhang, Ning, Su, Quan-ping, Zhang, Wei-xia, Shi, Nian-jun, Zhang, Hao, Wang, Ling-ping, Liu, Zhong-kai, Li, Ke-zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611550/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1600476
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