Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT

In the endoplasmic reticulum (ER), a protein quality control system facilitates the efficient folding of newly synthesised proteins. In this system, a series of N-linked glycan intermediates displayed on the protein surface serve as quality tags. The ER folding-sensor enzyme UDP-glucose:glycoprotein...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Satoh, Tadashi, Song, Chihong, Zhu, Tong, Toshimori, Takayasu, Murata, Kazuyoshi, Hayashi, Yugo, Kamikubo, Hironari, Uchihashi, Takayuki, Kato, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610325/
https://ncbi.nlm.nih.gov/pubmed/28939828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12283-w
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