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Structural Fluctuations of the Human Proteasome α7 Homo-Tetradecamer Double Ring Imply the Proteasomal α-Ring Assembly Mechanism

The 20S proteasome, which is composed of layered α and β heptameric rings, is the core complex of the eukaryotic proteasome involved in proteolysis. The α7 subunit is a component of the α ring, and it self-assembles into a homo-tetradecamer consisting of two layers of α7 heptameric rings. However, t...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Song, Chihong, Satoh, Tadashi, Sekiguchi, Taichiro, Kato, Koichi, Murata, Kazuyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123668/
https://ncbi.nlm.nih.gov/pubmed/33926037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094519
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