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Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release

BACKGROUND AND PURPOSE: Perivascular adipose tissue (PVAT) surrounds most blood vessels and secretes numerous active substances, including adiponectin, which produce a net anticontractile effect in healthy individuals. AMPK is a key mediator of cellular energy balance and may mediate the vascular ef...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Almabrouk, Tarek A M, Ugusman, Azizah B, Katwan, Omar J, Salt, Ian P, Kennedy, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610155/
https://ncbi.nlm.nih.gov/pubmed/27668984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13633
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