High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion

Background and aim: Perivascular adipose tissue (PVAT) positively regulates vascular function through production of factors such as adiponectin but this effect is attenuated in obesity. The enzyme AMP-activated protein kinase (AMPK) is present in PVAT and is implicated in mediating the vascular effe...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Almabrouk, Tarek A. M., White, Anna D., Ugusman, Azizah B., Skiba, Dominik S., Katwan, Omar J., Alganga, Husam, Guzik, Tomasz J., Touyz, Rhian M., Salt, Ian P., Kennedy, Simon
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812172/
https://ncbi.nlm.nih.gov/pubmed/29479319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00051
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