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Perivascular adipose tissue-derived adiponectin activates BK(Ca) channels to induce anticontractile responses

This study aims to identify the potential mechanisms by which perivascular adipose tissue (PVAT) reduces tone in small arteries. Small mesenteric arteries from wild-type and large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel knockout mice were mounted on a wire myograph in the presence and abs...

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Autors principals: Lynch, Fiona M., Withers, Sarah B., Yao, Zhihong, Werner, Matthias E., Edwards, Gill, Weston, Arthur H., Heagerty, Anthony M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602769/
https://ncbi.nlm.nih.gov/pubmed/23292715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00697.2012
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