Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development

The three-dimensional arrangement of the human genome comprises a complex network of structural and regulatory chromatin loops important for coordinating changes in transcription during human development. To better understand the mechanisms underlying context-specific 3D chromatin structure and tran...

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Udgivet i:Mol Cell
Main Authors: Phanstiel, Douglas H, Van Bortle, Kevin, Spacek, Damek, Hess, Gaelen T, Shamim, Muhammad Saad, Machol, Ido, Love, Michael I, Aiden, Erez Lieberman, Bassik, Michael C, Snyder, Michael P
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610110/
https://ncbi.nlm.nih.gov/pubmed/28890333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.08.006
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