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Clinical strategies for acquired epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small-cell lung cancer patients

Epidermal growth factor receptor (EGFR) mutations (EGFRm(+)) occur in 10–35% of non-small-cell lung cancer (NSCLC) cases and confer sensitivity to EGFR tyrosine kinase inhibitors (TKIs). EGFR TKIs are standard treatments for NSCLC patients harboring EGFR exon 19 deletions or exon 21 L858R point muta...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Dong, Lijun, Lei, Dan, Zhang, Haijun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610029/
https://ncbi.nlm.nih.gov/pubmed/28969097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19925
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