Clinical Definition of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer

Ten percent of North American patients with non–small-cell lung cancer have tumors with somatic mutations in the gene for the epidermal growth factor receptor (EGFR). Approximately 70% of patients whose lung cancers harbor somatic mutations in exons encoding the tyrosine kinase domain of EGFR experi...

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Bibliographische Detailangaben
Hauptverfasser: Jackman, David, Pao, William, Riely, Gregory J., Engelman, Jeffrey A., Kris, Mark G., Jänne, Pasi A., Lynch, Thomas, Johnson, Bruce E., Miller, Vincent A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2010
Schlagworte:
Special Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870288/
https://ncbi.nlm.nih.gov/pubmed/19949011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.24.7049
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