ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

Epithelial-mesenchymal transition (EMT) is one mechanism of acquired resistance to inhibitors of the epidermal growth factor receptor-tyrosine kinases (EGFR-TKIs) in non-small cell lung cancer (NSCLC). The precise mechanisms of EMT-related acquired resistance to EGFR-TKIs in NSCLC remain unclear. We...

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Vydáno v:PLoS One
Hlavní autoři: Yoshida, Takeshi, Song, Lanxi, Bai, Yun, Kinose, Fumi, Li, Jiannong, Ohaegbulam, Kim C., Muñoz-Antonia, Teresita, Qu, Xiaotao, Eschrich, Steven, Uramoto, Hidetaka, Tanaka, Fumihiro, Nasarre, Patrick, Gemmill, Robert M., Roche, Joëlle, Drabkin, Harry A., Haura, Eric B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720447/
https://ncbi.nlm.nih.gov/pubmed/26789630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147344
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