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ZEB-1, a Repressor of the Semaphorin 3F Tumor Suppressor Gene in Lung Cancer Cells

SEMA3F is a secreted semaphorin with potent antitumor activity, which is frequently downregulated in lung cancer. In cancer cell lines, SEMA3F overexpression decreases hypoxia-induced factor 1α protein and vascular endothelial growth factor mRNA, and inhibits multiple signaling components. Therefore...

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Autors principals: Clarhaut, Jonathan, Gemmill, Robert M, Potiron, Vincent A, Ait-Si-Ali, Slimane, Imbert, Jean, Drabkin, Harry A, Roche, Joëlle
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631140/
https://ncbi.nlm.nih.gov/pubmed/19177200
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