BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands

Using syngeneic BALB/c mouse breast cancer models, we show that the chromatin remodeling subunit bromodomain PHD finger transcription factor (BPTF) suppresses natural killer (NK) cell antitumor activity in the tumor microenvironment (TME). In culture, BPTF suppresses direct natural cytotoxicity rece...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Mayes, Kimberly, Elsayed, Zeinab, Alhazmi, Aiman, Waters, Michael, Alkhatib, Suehyb G., Roberts, Mark, Song, Carolyn, Peterson, Kristen, Chan, Vivian, Ailaney, Nikhil, Malapati, Pumoli, Blevins, Tana, Lisnić, Berislav, Dumur, Catherine I., Landry, Joseph W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610007/
https://ncbi.nlm.nih.gov/pubmed/28969075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17834
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