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Breast cancer suppression by aplysin is associated with inhibition of PI3K/AKT/FOXO3a pathway

Aplysin, a bromosesquiterpene isolated from Aplysia kurodai, was explored as a potential anti-breast cancer agent by us. However, the mechanisms underlying the anticarcinogenic effect of aplysin remain unclear. Here, aplysin was found to remarkably suppress tumor growth in vivo, inhibit cell prolife...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Xinling, Zhuang, Tingting, Liang, Zhengyan, Li, Li, Xue, Meilan, Liu, Jia, Liang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609973/
https://ncbi.nlm.nih.gov/pubmed/28969041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19209
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