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Quercetin prevents primordial follicle loss via suppression of PI3K/Akt/Foxo3a pathway activation in cyclophosphamide-treated mice

BACKGROUND: Chemotherapy improves the survival rates of patients with various cancers but often causes some adverse effects, including ovarian damage, characterised by a decrease in primordial follicle stockpiles. Recent studies have revealed that chemotherapy may stimulate the PI3K signalling pathw...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Li, Jianghui, Long, Hui, Cong, Yanyan, Gao, Hongyuan, Lyu, Qifeng, Yu, Sha, Kuang, Yanping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063466/
https://ncbi.nlm.nih.gov/pubmed/33892727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-021-00743-y
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