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Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

BACKGROUND: Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential mechanism for patients receiving chemotherapy....

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Detalhes bibliográficos
Publicado no:J Ovarian Res
Main Authors: Zhou, Linyan, Xie, Yanqiu, Li, Song, Liang, Yihua, Qiu, Qi, Lin, Haiyan, Zhang, Qingxue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559863/
https://ncbi.nlm.nih.gov/pubmed/28814333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-017-0350-3
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