Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

BACKGROUND: Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential mechanism for patients receiving chemotherapy....

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Dades bibliogràfiques
Publicat a:J Ovarian Res
Autors principals: Zhou, Linyan, Xie, Yanqiu, Li, Song, Liang, Yihua, Qiu, Qi, Lin, Haiyan, Zhang, Qingxue
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559863/
https://ncbi.nlm.nih.gov/pubmed/28814333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-017-0350-3
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