EGFR or HER2 inhibition modulates the tumor microenvironment by suppression of PD-L1 and cytokines release

BACKGROUND: Characteristics of tumor microenvironment have been suggested as predictive markers of anti-EGFR or anti-HER2 treatment response. However, the effect of EGFR/HER2 signal blockade on the tumor immune microenvironment is unclear. METHODS: EGFR/HER2 pathway signaling and PD-L1 expression in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Suh, Koung Jin, Sung, Ji Hea, Kim, Jin Won, Han, Song-Hee, Lee, Hye Seung, Min, Ahrum, Kang, Mi Hyun, Kim, Ji Eun, Kim, Ji-Won, Kim, Se Hyun, Lee, Jeong-Ok, Kim, Yu Jung, Lee, Keun-Wook, Kim, Jee Hyun, Bang, Soo-Mee, Im, Seock-Ah, Lee, Jong Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609971/
https://ncbi.nlm.nih.gov/pubmed/28969039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19194
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