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The Role of Biomarkers and Surrogate End Points in Drug Development for Neonatal Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a rare disease in newborns, infants, and children. It is associated with significant morbidity and mortality, but has limited treatment options. Except for inhaled nitric oxide, which is approved for persistent pulmonary hypertension of the newborn (PPHN), no...

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Detalhes bibliográficos
Publicado no:Neoreviews
Main Authors: Sun, Haihao, Stockbridge, Norman, Ariagno, Ronald L., Murphy, Dianne
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609821/
https://ncbi.nlm.nih.gov/pubmed/28943808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/neo.17-2-e87
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