HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness

Previously, we showed that Killer Immunoglobulin-like Receptor (KIR)3DS1 homozygotes (hmz) are more frequent in HIV exposed seronegative (HESN) than in recently HIV infected (HIV+) individuals. KIR3DS1 encodes an activating Natural Killer (NK) cell receptor (NKR). The link between KIR genotype and H...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jackson, Elise, Zhang, Cindy Xinyu, Kiani, Zahra, Lisovsky, Irene, Tallon, Benjamin, Del Corpo, Alexa, Gilbert, Louise, Bruneau, Julie, Thomas, Réjean, Côté, Pierre, Trottier, Benoit, LeBlanc, Roger, Rouleau, Danielle, Tremblay, Cécile, Tsoukas, Christos M., Routy, Jean-Pierre, Ni, Xiaoyan, Mabanga, Tsoarello, Bernard, Nicole F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609756/
https://ncbi.nlm.nih.gov/pubmed/28938026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185160
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